College of Health Sciences

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    Seroprevalence of Transfusion Infections Among Prospective Blood Donors in a District Hospital in Abuja, Nigeria
    (Nile University of Nigeria, 2025-01-02) Nwankwo Chizoba Gloria; Sanni Emmanuel Oladipo; Okudo Adaora Chinwendu; Eseigbe, P.; Ezike Kevin Nwabueze
    Background: Blood transfusion plays a crucial role in medical practices. However, blood transfusion safety remains a public health concern in developing countries due to the high prevalence of Transfusion Transmissible Infections (TTIs) among blood donors. Methods: This was a retrospective cross-sectional study involving data obtained from prospective blood donors’ records at the blood bank of Asokoro District Hospital (ADH), Abuja, Nigeria, from 01 January 2021 to 31 December 2021. The records comprised results of screening for TTIs, namely Human Immunodeficiency Virus (HIV), Hepatitis B virus (HBV), Hepatitis C virus (HCV), and syphilis. Screening was performed using rapid test kits. Data was analyzed with the SPSS 23.0 statistical software. Results: A total of 1,507 blood donor data were analyzed. The age range of the donors was 17 to 67 years. TTIs amongst donors in ADH, Abuja was HCV 4.2%, HBV 4.1%, Syphilis 1.0%, and HIV 0.9% respectively. Conclusion: There is a need for counselling amongst positive patients after blood transfusion screening, and referral to the relevant clinics for management. There is also a need to create effective public health interventions towards HCV infection which had the highest prevalence among blood donors.